Anales de la RANM

34 A N A L E S R A N M R E V I S T A F U N D A D A E N 1 8 7 9 UTEROGLOBINA Y IL2R ASOCIADO CON AR Oreiro N, et al. An RANM. 2023;140(01):31 - 42 Tabla 1.- Características de los genes evaluados y sus polimorfismos SNP# Símbolo Gen Nombre del gen Polimorfismo ID (rs) 1 RUNX1 Runx-related Transcription Factor 1 G2677T rs2268277 2 PADI4 Peptidylarginine Deiminase type IV G55S rs11203366 3 PADI4 Peptidylarginine Deiminase type IV V82A rs11203367 5 PADI4 Peptidylarginine Deiminase type IV L117L rs1748033 7 VEGF Vascular Endothelial Growth Factor C634G rs2010963 8 PDCD1 Programmed Cell Death 1 C+872T rs2227981 9 VDR Vitamin D receptor AposVS7+283(b>B) rs1544410 10 NFKBIL1 NF of k light pp enhancer Bcells inhibitor-like 1 T-62A rs2071592 11 PARP1 Poly ADP-ribose polymerase 1 C1362T rs7531668 12 CTLA4 Cytotoxic T-lymphocyte antigen 4 A49G rs231775 15 IL18 Interleukin 18 G-137C rs187238 16 TP53 Tumor Protein p53 codon 72 rs1042522 17 TNFR1 Tumor Necrosis Factor Receptor 1 36 A/A rs1139417 18 GSTM1 Glutathione S-transferase M1 null allele not available 19 GSTT1 Glutathione S-transferase T1 null allele not available 20 TNFR2 Tumor Necrosis Factor Receptor 2 T587G rs1061622 21 MMP3 Matrix Metalloproteinase 3 113G/A (R30Q) rs3025058 23 NAT2 N-Acetyltransferase 2 282C>T rs1041983 24 NAT2 N-acetyltransferase 2 590G>A rs1799930 25 PTPN22 Protein-tyrosine phosphatase, non-receptor 2 1858C/T rs2476601 26 TPSN Tapasin Arg260Thr rs2071888 27 FCRL3 Fc receptor-like protein 3 -169 T/C rs7528684 29 SLC22A4 Solute Carrier Family 22 A4 1672C-T 1050152 31 TNFA Tumor necrosis factor-alpha -238 G>A rs361525 32 TNFA Tumor necrosis factor-alpha C-308T rs1800629 33 IL1RN The IL-1 receptor antagonist T2018C rs419598 34 IL1RN The IL-1 receptor antagonist T2073C,in2 (IL-1RN*2) rs423904 35 MTHFR Methylenetetrahydrofolate Reductase C677T rs1801133 36 TPMT Thiopurine s-Methyltransferase G460A rs2842934 38 TNFA Tumor necrosis factor-alpha -857C/T rs1799724 39 SCGB1A1 Uteroglobin A587G rs3741240 40 ATIC Carboxamide ribonucleotide formyltransferase 347GG rs2372536 41 TIM3 Tcell immunoglobulin domain mucin domain 3 -547T>C rs10515746 42 TIM3 Tcell immunoglobulin domain mucin domain 3 4259G>T rs1036199 43 NOTCH4 Notch homolog 4 intron T/G rs2269418 44 MDR-1 Multidrug Resistance Protein 1 C3435T rs2235048 45 MICA MHC class I chain-related gene A Intron C/T rs2252223 46 IL4R Interleukin 4 Receptor Q551R rs1801275 47 MICA MHC class I chain-related gene A Intron G/T not available 48 IL10 Interleukin 10 -A2849G rs6703630 49 IL10 Interleukin 10 1082A>G rs1800896 50 TNFA Tumor necrosis factor-alpha C-308T rs1800629 51 IL10 Interleukin 10 -1087 (GG) rs1800896 52 FGB Fibrinogen B beta polypeptide G455A rs1800790