Anales de la RANM

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Gene- tic factors associated with rheumatoid arthri- tis and systemic vasculitis: Evaluation of a panel of polymorphisms. Dis Markers. 2009; 27(5): 217-223. 19. Kim YS, Kang D, Kwon DY et al. Uteroglobin gene polymorphisms affect the progression of immunoglobulin A nephropathy by mo- dulating the level of uteroglobin expression. Pharmacogenetics. 2001; 11(4): 299-305. 20. Liao W, Lin JX, Leonard WJ. IL-2 family cyto- kines: New insights into the complex roles of IL-2 as a broad regulator of T helper cell differentiation. Curr Opin Immunol. 2011; 23(5): 598-604. 21. Kurreeman FA, Daha NA, Chang M et al. As- sociation of IL2RA and IL2RB with rheuma- toid arthritis: a replication study in a Dutch population. Ann Rheum Dis. 2009; 68(11): 1789-1790. 22. De Rycke L, Peene I, Hoffman IE et al. Rheu- matoid factor and anticitrullinated protein antibodies in rheumatoid arthritis: Diag- nostic value, associations with radiological progression rate, and extra-articular mani- festations. Ann Rheum Dis. 2004; 63(12): 1587-1593. 23. Ewa Berglin, Leonid Padyukov, Ulf Sundin et al. A combination of autoantibodies to cyclic citrullinated peptide (CCP) and HLA-DRB1 locus antigens is strongly associated with fu- ture onset of rheumatoid arthritis. Arthritis Res Ther. 2004; 6(4): R303-R308. 24. Meyer O, Labarre C, Dougados M et al. Anti- citrullinated protein/peptide antibody assays in early rheumatoid arthritis for predicting five year radiographic damage. Ann Rheum Dis. 2003; 62(2): 120-126. 25. Nielen MM, van der Horst AR, van der Horst- Bruinsma IE et al. Antibodies to citrullina- ted human fibrinogen (ACF) have diagnostic and prognostic value in early arthritis. Ann Rheum Dis. 2005; 64(8): 1199-1204. 26. Van der Woude D, Syversen SW, van der Voort EI et al. The ACPA isotype profile re- flects long-term radiographic progression in rheumatoid arthritis. Ann Rheum Dis. 2010; 69(6):1110-1116. 27. Van der Helm-van Mil AH, Verpoort KN, Breedveld FC, Toes RE, Huizinga TW. An- tibodies to citrullinated proteins and diffe- rences in clinical progression of rheumatoid arthritis. Arthritis Res Ther. 2005; 7(5): R949-R958. 28. Ahmed MM, Obaid Al-Ruhaimi KA, Mo- hammed SH. Evaluation of the rheumatoid factors of the IgG, IgM and IgA isotypes as prognostic parameters for rheumatoid arthri- tis among Iraqi patients. Indian J Pathol Mi- crobiol. 2010; 53(3): 439-444. 29. Berglin E, Johansson T, Sundin U et al. Ra- diological outcome in rheumatoid arthritis is predicted by presence of antibodies aga- inst cyclic citrullinated peptide before and at disease onset, and by IgA-RF at disease onset. Ann Rheum Dis. 2006; 65(4): 453- 458. 30. Mewar D, Coote A, Moore DJ et al. Inde- pendent associations of anti-cyclic citrulli- nated peptide antibodies and rheumatoid factor with radiographic severity of rheu- matoid arthritis. Arthritis Res Ther. 2006; 8(4): R128. 31. Lindqvist E, Jonsson K, Saxne T, Eberhardt K. Course of radiographic damage over 10 years in a cohort with early rheumatoid ar- thritis. Ann Rheum Dis. 2003; 62(7): 611- 616. 32. Drossaers-Bakker KW, de Buck M, van Zeben D, Zwinderman AH, Breedveld FC, Hazes JM. Long-term course and outcome of functional capacity in rheumatoid arthritis: the effect of disease activity and radiologic damage over time. Arthritis Rheum. 1999; 42(9): 1854- 1860. 33. Combe B, Dougados M, Goupille P et al. Prognostic factors for radiographic damage in early rheumatoid arthritis: a multiparame- ter prospective study. Arthritis Rheum. 2001; 44(8): 1736-1743. 34. Guillemin F , Gérard N, van Leeuwen M, Smedstad LM, Kvien TK, van den Heuvel W; EURIDISS Group. Prognostic factors for joint destruction in rheumatoid arthritis: a pros- pective longitudinal study of 318 patients. J Rheumatol. 2003; 30(12): 2585-2589. 35. Dixey J, Solymossy C, Young A; Early RA Stu- dy. 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