Anales de la RANM

131 A N A L E S R A N M R E V I S T A F U N D A D A E N 1 8 7 9 THE IMPACT OF MIGRATION IN FIRST-EPISODE PSYCHOSIS López Ortega A et al. An RANM. 2024;141(02): 126 - 133 However, it was found that sex alone signifi- cantly predicted PANSS Negative in 1 st genera- tion migrants (B = -3.592, p = 0.041). For instance, in the 1 st generation migrant group, women were estimated to have a mean score of -3.592 points lower on the PANSS Negative than men in our migrant FEP group. The remaining variables (i.e childhood adversities, age, and age at migration) did not exhibit a significant effect on the PANSS Negative scale in this group. DISCUSSION In this study, we investigated the impact of migration on the clinical presentation of first- episode psychosis. Additionally, we explored some of the variables that might contribute to the symptomatology in FEP first-generation migrant individuals. Our results revealed more severe negative symptoms in first-generation migrants than in non-migrants at the baseline clinical interview. First generation migrants were found to report higher levels of childhood adversity than non-migrants. According to our findings, sex emerges as a predictive factor for negative symptoms among first-generation migrants, with men having higher scores. Several studies have previously demonstrated that migration experience influences the clinical characteristics of psychosis (3). Congruent with this notion, our results highlight the difference in negative symptoms severity between migrants and non-migrants at the time of presentation of the FEP. However, these results are not aligned with those of previous studies that showed more severity of positive symptoms at first contact in first-genera- tion migrant groups (8), or no differences in any clinical scale between migrants and non-migrants (13). Nevertheless, the assessment of negative symptoms is complex and requires a specific training. Therefore, the hostile environment faced by first-generation migrants and the ethnic variabi- lity may lead the examiner to interpret greater negative symptomatology on them compared to non-migrants (26). Consistent with previous literature, we found a greater cumulative exposure to childhood adversity in first-generation migrants with FEP (25). These findings have been previously linked to an increased risk of psychosis in this group (27). Regarding its plausible impact on clinical presentation, negative symptoms were not associated with total childhood adversities as assessed in our study. This might be congruent with previous research suggesting that childhood adversities are associated with greater severity of hallucinations and delusions (28). Table 2. T-test on clinical scales. Native (N = 249) 1st generation migrants (N = 114) Mean SD Mean SD t p value Young Mania Rating Scale Total Score 4,14 6,14 4,44 5,73 -0.435 0,664 Hamilton Depression Rating Scale Total Score 10,50 9,12 10,62 6,71 -0.108 0,914 PANSS Negative total 16,35 6,94 18,58 8,21 -2,602 0,010 PANSS Positive total 14,13 6,628 15,37 6,88 -16118 0,106 PANSS General total 31,70 11,59 32,77 11,24 -0,821 0,412