Anales de la RANM

81 A N A L E S R A N M R E V I S T A F U N D A D A E N 1 8 7 9 COVID-19 Y DAÑO VASCULAR Sánchez Ferrer CF, et al. An RANM. 2025;142(01): 73 - 81 45. Yu C, Xiao JH. The Keap1-Nrf2 System: A me- diator between oxidative stress and aging. Oxid Med Cell Longev. 2021:2021: 6635460. doi: 10.1155/2021/6635460. 46. Romero A, San Hipólito-Luengo Á, Villa- lobos LA, et al. The angiotensin-(1-7)/Mas receptor axis protects from endothelial cell senescence via klotho and Nrf2 activation. Aging Cell. 2019;18(3):e12913. doi: 10.1111/ acel.12913. 47. Peiró C, Vallejo S, Gembardt F, et al. Complete blockade of the vasorelaxant effects of angio- tensin-(1-7) and bradykinin in murine micro- vessels by antagonists of the receptor Mas. J Physiol. 2013;591(9): 2275-85. doi: 10.1113/ jphysiol.2013.251413. 48. Richter B, Haller J, Haffner D, et al. Klotho modulates FGF23-mediated NO synthesis and oxidative stress in human coronary artery en- dothelial cells. Pflugers Arch. 2016;468(9): 1621-35. doi: 10.1007/s00424-016-1858-x. 49. Blanco-Melo D, Nilsson-Payant BE, Liu WC, et al. Imbalanced host response to SARS- CoV-2 drives development of COVID-19. Cell. 2020;181(5):1036-1045.e9. doi: 10.1016/j. cell.2020.04.026. 50. Rodrigues TS, de Sá KSG, Ishimoto AY, et al. Inflammasomes are activated in response to SARS-cov-2 infection and are associated with COVID-19 severity in patients. J Exp Med. 2021;218(3):e20201707. doi: 10.1084/ jem.20201707. Si desea citar nuestro artículo: Sánchez Ferrer CF, Villacampa Calvo A, Shamoon L, Lorenzo Gon- zález O, Peiró Vallejo C. Citoquinas y particular virales como in- ductoras de daño vascular en COVID-19. An RANM. 2025;142(01): 73– 81. DOI: 10.32440/ar.2025.142.01. rev07