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81 A N A L E S R A N M R E V I S T A F U N D A D A E N 1 8 7 9 MORTALIDAD EN LA INTOXICACIÓN POR PARAQUAT Chinchilla-Escobar, et al. An RANM. 2021;138(01): 72 - 81 by measurement of the plasma Paraquat con- centration. Qjm. 2009; 102(4): 251-259. 24. Proudfoot AT, Stewart MS, Levitt T, Widdop B. Paraquat poisoning: significance of plasma- Paraquat concentrations. Lancet [Internet]. 1979; 314(8138): 330-332. Available from: https://linkinghub.elsevier.com/retrieve/pii/ S0140673679903453 25. Jones AL, Elton R, Flanagan R. Multiple logistic regression analysis of plasma Paraquat concen- trations as a predictor of outcome in 375 cases of Paraquat poisoning. QJM [Internet]. 1999; 92(10): 573-578. Available from: http://www. ncbi.nlm.nih.gov/pubmed/10627878 26. Sawada Y, Yamamoto I, Hirokane T, Nagai Y, Satoh Y, Ueyama M. Severity index of Pa- raquat poisoning. Lancet [Internet]. 1988; 1(8598):1333. Available from: http://www.ncbi . nlm.nih.gov/pubmed/2897577 27. Zhang Y, Yu B, Wang N, Li T. Acute poisoning in Shenyang, China: a retrospective and des- criptive study from 2012 to 2016. BMJ Open. 2018; 8(8): 1-11. 28. Weng CH, Chen HH, Hu CC, et al. Predictors of acute kidney injury after Paraquat intoxication. Oncotarget. 2017; 8(31): 51345-51354. 29. Wang WJ, Zhang LW, Feng SY, Gao J, Li Y. Se- quential organ failure assessment in predicting mortality after Paraquat poisoning: a meta- analysis. Sun Q, editor. PLoS One [Internet]. 2018; 13(11): e0207725. Available from: http:// dx.plos.org/10.1371/journal.pone.0207725 30. Sun B, Chen YG. Advances in the mechanism of Paraquat-induced pulmonary injury. Eur Rev Med Pharmacol Sci. 2016; 20(8): 1597-1602. 31. Villanueva Cañadas E y Hernández Jerez A. In- toxicación por plaguicidas. En: Villanueva Ca- ñadas Enrique, ed. Gisbert Calabuig Medicina legal y toxicológica. 7ª ed. Barcelona : Elsevier; 2018. p. 1011-1020. 32. Yang CJ, Lin JL, Lin-Tan DT, et al. Spectrum of toxic hepatitis following intentional Paraquat ingestion: Analysis of 187 cases. Liver Int. 2012; 32(9): 1400-1406. 33. Lee EY, Hwang KY, Yang JO, Hong SY. Predic- tors of survival after acute Paraquat poisoning. Toxicol Ind Health. 2002; 18(4): 201-206. 34. Hong SY, Yang DH, Hwang KY. Associations between laboratory parameters and outcome of Paraquat poisoning. Toxicol Lett. 2000; 118(1- 2): 53-59. 35. Lee JH, Hwang SY, Kim HR, et al. Effective- ness of the sequential organ failure assessment, acute physiology and chronic health evalua- tion II, and simplified acute physiology score II prognostic scoring systems in Paraquat-poi- soned patients in the intensive care unit. Hum Exp Toxicol. 2017; 36(5): 431-437. 36. Chen H, Hu L, Li H, et al. An effective machine learning approach for prognosis of Paraquat poi- soning patients using blood routine indexes. Ba- sic Clin Pharmacol Toxicol. 2017; 120(1): 86-96. 37. Chang MW, Chang SS, Chien-Chang LEE, Sheu BF, Young YR. Hypokalemia and hypothermia are associated with 30-day mortality in patients with acute Paraquat poisoning. Am J Med Sci. 2008; 335(6): 451-456. DECLARACIÓN DE TRANSPARENCIA Los autores/as de este artículo declaran no tener ningún tipo de conflicto de intereses respecto a lo expuesto en el presente trabajo. Si desea citar nuestro artículo: Chinchilla-Escobar EC, Zapata-Ospina JP, Peña-Acevedo LM, Pineda-Álvarez M. Evaluación longitudinal de los factores asocia- dos con la mortalidad en la intoxicación por paraquat. An RANM. 2021;138(01): 72– 81. DOI: 10.32440/ar.2021.138.01. rev08