Anales de la RANM

149 A N A L E S R A N M R E V I S T A F U N D A D A E N 1 8 7 9 Pozo MA, et al. An RANM. 2022;139(02): 140 - 149 MODELOS EXPERIMENTALES DE EPILEPTOGÉNESIS 39. Mahmoud S, Gharagozloo M, Simard C, Gris D. Astrocytes maintain glutamate homeostasis in the CNS by controlling the balance between glu- tamate uptake and release. Cells. 2019; 8(2):184. 40. Bar‐Klein G, Klee R. Brandt C et al. Isoflura- ne prevents acquired epilepsy in rat models of temporal lobe epilepsy. Ann Neurol. 2016, 80(6), 896-908. 41. Allen NJ, Barres BA. Glia-more than just brain glue. Nature 2009; 457: 675. 42. Marina N, Turovsky E, Christie IN et al. Brain metabolic sensing and metabolic signaling at the level of an astrocyte. Glia. 2018; 66:1185. 43. Bélanger M, Allaman I, Magistretti PJ. Brain ener- gy metabolism: focus on astrocyte-neuron metabo- lic cooperation. Cell Metab. 2011; 14(6):724. 44. Armbruster BN, Li X, Pausch MH, Herlitze S, Roth BL. Evolving the lock to fit the key to create a family of G protein-coupled receptors potently activated by an inert ligand. Proc Natl Acad Sci USA. 2007; 104 (12) 5163. 45. Bonder DE, McCarthy KD. Astrocytic Gq-GP- CR-Linked IP3R-Dependent Ca2+ Signaling Does Not Mediate Neurovascular Coupling in Mouse Visual Cortex In Vivo. J Neurosci. 2014; 34 (39): 13139. 46. Shen W, Chen S, Liu Y, Han P, Ma T, Zeng LH. Chemogenetic manipulation of astrocytic activi- ty: Is it possible to reveal the roles of astrocytes? Biochem Pharmacol. 2021; 186:114457. 47. Jones ME, Paniccia JE, Lebonville CL, Reissner KJ & Lysle DT. Chemogenetic Manipulation of Dorsal Hippocampal Astrocytes Protects Aga- inst the Development of Stress-enhanced Fear Learning. Neuroscience. 2018; 388:45-56. 48. Lim EY, Ye L & Paukert M. Potential and Reali- zed Impact of Astroglia Ca2+ Dynamics on Cir- cuit Function and Behavior. Front. Cell. Neuros- ci. 2021; 15:682888. 49. MacDonald AJ, Holmes FE, Beall C, Pickering AE, Ellacott KLJ. Regulation of food intake by astrocytes in the brainstem dorsal vagal com- plex. Glia 2020; 68(6):1241. 50. Nwachukwu KN, Evans WA, Sides TR, Trevisani CP, Davis A, Marshall SA. Chemogenetic mani- pulation of astrocytic signaling in the basolate- ral amygdala reduces binge-like alcohol con- sumption in male mice. J Neurosci Res. 2021; 99:1957. DECLARACIÓN DE TRANSPARENCIA Los autores/as de este artículo declaran no tener ningún tipo de conflicto de intereses respecto a lo expuesto en el presente trabajo. Si desea citar nuestro artículo: Pozo MA, Hernández N, Bascuñana P, de la Rosa RF, Gómez F, Mar- tín ED, García-García L. Modelos experimentales en el estudio de la epileptogénesis. An RANM. 2022;139(02): 140– 149. DOI: 10.32440/ar.2022.139.02. rev04