Anales de la RANM

54 A N A L E S R A N M R E V I S T A F U N D A D A E N 1 8 7 9 TMR O RPNI EN PACIENTES CON AMPUTACIÓN DE EXTREMIDADES An RANM. 2026;143(01): 48 - 55 Gurpegui Gámiz D, et al. 4. Cheesborough J, Smith L, Kuiken T, Dumanian G. Targeted Muscle Reinnervation and Advanced Prosthetic Arms. Semin Plast Surg. 2015;29:62-72. 5. Kuiken TA, Barlow AK, Hargrove LJ, Dumanian GA. Targeted Muscle Reinnervation for the Upper and Lower Extremity. Tech Orthop. 2017;32:109- 116. 6. Henderson JT, Koenig ZA, Climov M, Gelman J. Demystifying Targeted Muscle Reinnervation: A Systematic Review of Nerve Transfers for the Lower Extremity. Plast Reconstr Surg Glob Open. 2023;11:e4894. 7. Hooper RC, Cederna PS, Brown DL, et al. Regene- rative Peripheral Nerve Interfaces for the Manage- ment of Symptomatic Hand and Digital Neuromas. Plast Reconstr Surg Glob Open. 2020;8:e2792. 8. Kubiak CA, Kemp SWP, Cederna PS. Regene- rative Peripheral Nerve Interface for Manage- ment of Postamputation Neuroma. JAMA Surg. 2018;153:681. 9. Walsh AR, Lu J, Rodriguez E, Diamond S, Sultan SM. The Current State of Targeted Muscle Reinner- vation: A Systematic Review. J Reconstr Microsurg. 2023;39:238-244. 10. Yuan M, Gallo M, Gallo L, et al. Targeted Muscle Reinnervation and Regenerative Peripheral Nerve Interfaces Versus Standard Management in the Treatment of Limb Amputation: A Systematic Review and Meta-Analysis. Plast Surg (Oakv). 2024;32:253-264. 11. Zimbulis AJ, An VVG, Symes M, et al. Targeted Muscle Reinnervation Compared to Standard Peripheral Nerve Management Following Amputa- tion: A Systematic Review and Meta-Analysis. Hand (N Y). 2025;20:1197-1206. 12. Mauch JT, Kao DS, Friedly JL, Liu Y. Targeted muscle reinnervation and regenerative peripheral nerve interfaces for pain prophylaxis and treatment: A systematic review. PM&R. 2023;15:1457-1465. 13. Hagiga A, Aly M, Gumaa M, Rehan Youssef A, Cubison T. Targeted muscle reinnervation in managing post-amputation related pain: A systematic review and meta-analysis. Pain Pract. 2023;23:922-932. 14. Higgins JPT, Thomas J, Chandler J, et al (editors). Cochrane Handbook for Systematic Reviews of Interventions version 6.5. Cochrane; 2024. Available from www.training.cochrane.org/handbook. 15. Higgins JPT, Lasserson T, Chandler J, et al. Methodological Expectations of Cochrane Intervention Reviews. Cochrane: London, Version February 2021. https://community.cochrane.org/ mecir-manual. 16. Page MJ, Moher D, Bossuyt PM, et al. PRISMA 2020 explanation and elaboration: updated guidance and exemplars for reporting systematic reviews. BMJ. 2021;n160. 17. Page MJ, McKenzie JE, Bossuyt PM, et al. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ. 2021;n71. 18. Covidence systematic review software, Veritas Health Innovation, Melbourne, Australia. Available at www.covidence.org . 19. ROBINS-I V2 Development Group. ROBINS-I V2. https://www.riskofbias.info/welcome/robins-i-v2 (accessed 12 December 2024). 20. Moola S, Munn Z, Tufanaru C, et al. Chapter 7: Systematic reviews of etiology and risk. In: Aromataris E, Munn Z (Editors). Joanna Briggs Institute Reviewer’s Manual. The Joanna Briggs Institute, 2017. Available from https://reviewers- manual.joannabriggs.org/. 21. Trauma, Burn, and Critical Care. J Am Coll Surg. 2024;239:S508-S557. 22. O’Brien AL, Jordan SW, West JM, Mioton LM, Dumanian GA, Valerio IL. Targeted Muscle Reinnervation at the Time of Upper-Extremity Amputation for the Treatment of Pain Severity and Symptoms. J Hand Surg. 2021;46:72.e1-72.e10. 23. Chang BL, Hill AL, Mondshine J, et al. Primary Targeted Muscle Reinnervation in Above-Knee Amputations in Patients with Unsalvageable Limbs from Limb-Threatening Ischemia or Infection. J Reconstr Microsurg. 2024;40:109-117. 24. Chang BL, Mondshine J, Attinger CE, Kleiber GM. Targeted Muscle Reinnervation Improves Pain and Ambulation Outcomes in Highly Comorbid Amputees. Plast Reconstr Surg. 2021;148:376-386. 25. Huffman A, Schneeberger S, Goodyear E, et al. Evaluating hip disarticulation outcomes in a 51-patient series. J Orthop. 2022;31:117-120. 26. Alexander JH, Jordan SW, West JM, et al. Targeted muscle reinnervation in oncologic amputees: Early experience of a novel institutional protocol. J Surg Oncol. 2019;120:348-358. 27. Smith TP, Cognetti DJ, Cook A, et al. Similar rates of reoperation for neuroma after transtibial amputa- tions with and without targeted muscle reinner- vation. OTA Int. 2024;7. Disponible en: https:// journals.lww.com/10.1097/OI9.0000000000000297. 28. Shammas RL, Azoury SC, Sergesketter AR, et al. Primary Targeted Muscle Reinnervation after Below-Knee Amputation Is Not Associated with an Increased Risk of Major or Minor Surgical Complications: A Multi-Institutional, Propen- sity Score–Matched Analysis. Plast Reconstr Surg. 2022;150:589-598. 29. Vaeth AM, Kochheiser M, Qin N, et al. D123. Advances in Neuroma Prevention: A Single Institu- tional Experience With TMR And TMRPNI in Lower Limb Amputees. Plast Reconstr Surg Glob Open. 2025;13:143-143. 30. Lu V, Zhou A, Krkovic M. Variation on a technique for the intra-muscular insertion of nerve endings to minimise neuropathic and residual pain in lower limb amputees: a retrospective cohort study. Eur J Orthop Surg Traumatol. 2022;33:1299-1306. 31. Valerio IL, Dumanian GA, Jordan SW, et al. Preemptive Treatment of Phantom and Residual Limb Pain with Targeted Muscle Reinnervation at the Time of Major Limb Amputation. J Am Coll Surg. 2019;228:217-226. 32. Mathieu L, Redais C, Diner C, et al. Curative and preemptive treatment of amputee pain by targeted muscle reinnervation: experience from a French military trauma center. Eur J Trauma Emerg Surg. 2025;51:37. 33. Li AT, Garcia N, Angliss M, Paul E, Gray S, Bruscino-Raiola F. Acute versus non-acute targeted muscle reinnervation for pain control following major limb amputation: A comparative study. J Plast Reconstr Aesthet Surg. 2024;94:229-237. 34. Pet MA, Ko JH, Friedly JL, Mourad PD, Smith DG. Does Targeted Nerve Implantation Reduce